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Efficacy of convalescent plasma for treatment of COVID-19 in Uganda
Journal: Authors:
BMJ Open Respiratory Research Bruce Kirenga, Pauline Byakika-Kibwika, Winters Muttamba, Alex Kayongo, Namakula Olive Loryndah, Levicatus Mugenyi, Noah Kiwanuka, John Lusiba, Angella Atukunda, Raymond Mugume, Francis Ssali, Henry Ddungu, Winceslaus Katagira, Rogers Sekibira, Cissy Kityo, Dorothy Kyeyune, Susan Acana, Hellen Aanyu-Tukamuhebwa, Wilberforce Kabweru, Fred Nakwagala, Bernard Sentalo Bagaya, Ivan Kimuli, Rebecca Nantanda, Esther Buregyeya. Baterana Byarugaba, Charles Olaro, Henry Mwebesa, Moses Lutaakome Joloba, Trishul Siddharthan, William Bazeyo August 2021
Publication date:
This article has received 30 academic citations, and garnered 25 citations in Policy Documents and Clinical Guidelines. See the full details below.
Real world impact
Top sources
Cited:
Citation source
Citations by source
in 25 documents (22 Policy Documents, 3 Clinical Guidance) from 4 countries with 5 different sources
Citing policy and guidance countries
Citing country
Intergovernmental Organization (IGO) Germany Switzerland USA
BMJ Impact Analytics Feb 2024
Academic impact
Altmetric 2024 and Dimensions 2024
Let’s hear from Dr Bruce J Kirenga, Makerere University Lung Institute, Uganda, about this 2021 article published in BMJ Open Respiratory Research “Open access publishing ensures publications are available to everyone, including scientists and policy makers in low resourced settings...”
Dr Bruce J Kirenga is Chief Research Scientist and founding Director of the Makerere University Lung Institute. He is also Associate Professor (Pulmonary Medicine) in the Department of Medicine, Makerere University.
What inspired you to pursue research in this particular area?
This research was driven by the need to have affordable therapeutics for COVID-19. At the time this research was done, there were no proven therapeutics for COVID-19, and those that were currently under development would certainly not be affordable for LMICs. There would thus be a need for a readily available and affordable therapeutics in our settings; and convalescent plasma seemed the viable option given we had a large pool of individuals that had recovered from COVID-19 and were willing to donate blood. How do you envision your research contributing to the broader field or addressing real-world issues? The research contributes to the body of evidence on the use of COVID-19 convalescent plasma in the treatment of COVID-19. The findings from this study were not different from findings from elsewhere, and this provided the scientific community with sufficient evidence against use of convalescent plasma to treat COVID-19 and consideration of other treatment options.
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What motivated you to publish your work in open access format?
An open access journal was chosen to ensure the findings were rapidly disseminated and consumed by everyone involved in the COVID-19 response regardless of their ability to pay. This was key given the COVID-19 pandemic was rapidly evolving and this information needed to be accessed and consumed rapidly. Further, this study had been conducted in a low resource setting and it was important the scientists and policy makers in these settings were able to access the findings freely. What do you see as the benefits of open access publishing compared to traditional publishing models? Open access publishing ensures the publications are available to everyone, including scientists and policy makers in low resourced settings – where access to such information could be limited if they must pay before access is granted. What advice would you give to other researchers who are considering publishing their work in open access formats for the first time? To consider open access journals with coverage in settings where their research could be more impactful.
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“An open access journal was chosen to ensure the findings were rapidly disseminated and consumed by everyone involved in the COVID-19 response regardless of their ability to pay.” Dr Bruce J Kirenga Makerere University Lung Institute, Uganda
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