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Supplemental material
Ann Rheum Dis
ILD on CT-scan , n (%)
15
6 (40%)
16
0 (0%)
24
5 (21%)
17
6 (35%)
Treatments - Prednisone, n (%)
15
0 (0%)
16
2 (13%)
16
1 (6%)
15
0 (0%)
- Cyclophosphamide, n (%)
15
0 (0%)
16
0 (0%)
16
0 (0%)
15
0 (0%)
- Mycophenolate mofetil, n (%)
15
0 (0%)
16
1 (6%)
16
0 (0%)
15
0 (0%)
- D-penicillamine, n (%)
15
0 (0%)
16
0 (0%)
16
2 (13%)
15
0 (0%)
- Azathioprine, n (%)
15
0 (0%)
16
0 (0%)
16
0 (0%)
15
0 (0%)
- Methotrexate, n (%)
15
0 (0%)
16
1 (6%)
16
1 (6%)
15
0 (0%)
Right-heart catheterization - mPAP (mmHg), mean ( SD) - PAWP (mmHg), mean ( SD) - CO (L/min), mean ( SD) - CI (L/min/m 2 ), mean ( SD)
44 ( 10) 10 ( 2) 4.9 ( 1.6) 2.7 ( 1.0) 8.5 ( 5.0)
37 ( 8) 10 ( 3)
15
/
/ /
24
/
/ /
15
/
/ /
24
/
/ /
4.6 ( 1.2) 2.5 ( 0.5) 6.2 ( 2.3)
15
/
/ /
24
/
/ /
15
/
/ /
18
/
/ /
- PVR (WU), mean ( SD)
15
/
/ /
24
/
/ /
¶
Supplementary Table 1. Detailed characteristics of patients from the discovery and validation cohorts ACA: anti-centromere antibodies; ANA: antinuclear antibodies; ATA: anti-topoisomerase I antibodies; Anti-U1RNP: anti-U1-ribonucleoprotein antibodies; BMI: body-mass index; BNP: brain natriuretic peptide; CI: cardiac index; CO: cardiac output; DLCO: diffusing capacity of the lung for carbon monoxide; eGFR: estimated glomerular filtration rate; FVC: forced vital capacity: ILD: interstitial lung disease: LVEF: left ventricular ejection fraction; mPAP: mean pulmonary arterial pressure; Nt-pro-BNP: N-terminal pro-brain natriuretic peptide; NYHA: New York Heart Association; PAH: pulmonary arterial hypertension; PAWP: pulmonary arterial wedge pressure; PVR: pulmonary vascular resistance; Q: quartile; RP: Raynaud phenomenon; SD: standard deviation; sPAP: systolic pulmonary arterial pressure; SSc: systemic sclerosis; WU: Wood unit; y: year; yo: year old.
2022;0:1–9. doi: 10.1136/ard-2022-223237 Ann Rheum Dis , et al. Sanges S
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