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Supplemental material
Ann Rheum Dis
Supplementary Material to: “ Impact of vaccination on post-acute sequelae of SARS CoV-2 infection in patients with rheumatic diseases ” by Patel, et al
Supplementary Table 1 . Persistent COVID-19 symptoms and other patient-reported outcomes in rheumatic disease patients following COVID-19 infection among those who completed surveys within 6 months of COVID-19 infection.
Breakthrough COVID-19
Non- breakthrough COVID-19 infection (N=41)
All rheumatic disease patients (N=147)
p-value
infection (N=106)
Days to acute symptom resolution or date of survey if symptoms ongoing, median [IQR] CDC Definition of PASC (COVID-19 symptoms lasting at least 28 days post-COVID-19 infection) WHO Definition of PASC (COVID- 19 symptoms lasting at least 90 days post-COVID-19 infection)*
21 (8, 60)
21 (8, 56)
25 (10, 91)
0.23
66 (45)
46 (43)
20 (49)
0.58
21 (29)
9 (24)
12 (33)
0.40
Pain (SF-MPQ) N
139
101
38
Median score [IQR]
4 (1, 9)
4 (1, 9)
4.5 (2, 9)
0.62
Pain rating index ordinal categories, n (%)
0.20
No pain
24 (16)
14 (13)
10 (24)
Mild pain
47 (32)
37 (35)
10 (24)
Discomforting, distressing, horrible, or excruciating pain
69 (47)
50 (47)
19 (46)
Fatigue (FSI) N
140
101
39
Median score [IQR]
54 (25, 82.5)
51 (23, 81)
58 (27, 85)
0.35
Functional status (mHAQ) N
142
103
39
Median score [IQR]
0.1 (0, 0.5)
0.1 (0, 0.5)
0.1 (0, 0.4)
0.51
Functional status categorical score, n (%)
1.00
Normal (<0.3)
89 (61)
64 (60)
25 (61)
Mild, moderate, or severe (0.3 to >1.8)
53 (36)
39 (37)
14 (34)
Health status (SF-12) PCS-12 score, median [IQR]
42.3 (33.4, 51.1)
43.6 (33.4, 52.5) 49 (41.3, 55)
40.8 (33.4, 47.5)
0.43
MCS-12 score, median [IQR] 0.79 CDC, Centers for Disease Control and Prevention; WHO, World Health Organization; FSI, Fatigue Symptom Inventory; mHAQ, modified Health Assessment Questionnaire; SF-12, Short-form 12-item 49.2 (39.4, 55.5) 49.9 (35.8, 57.6)
2022;0:1–9. doi: 10.1136/ard-2022-223439 Ann Rheum Dis , et al. Patel NJ
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