2023 Rheumatology at BMJ

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Supplemental material

Ann Rheum Dis

Supplementary Table 4 . Persistent COVID-19 symptoms and other patient-reported outcomes in rheumatic disease patients following COVID-19 infection among those who did not require hospitalization for COVID-19 infection. All rheumatic disease Breakthrough COVID-19

Non- breakthrough COVID-19 infection (N=134)

p-value

patients (N=244)

infection (N=110) 21 (8, 51)

Days to acute symptom resolution or date of survey if symptoms ongoing, median [IQR] CDC Definition of PASC (COVID-19 symptoms lasting at least 28 days post- COVID-19 infection) WHO Definition of PASC (COVID-19 symptoms lasting at least 90 days post- COVID-19 infection)*

21 (10, 84)

25 (10, 176)

0.01

112 (46)

46 (42)

66 (49)

0.25

57 (33)

10 (23)

47 (36)

0.12

Pain (SF-MPQ) N

224

106

118

Median score [IQR]

4 (2, 10)

4 (1, 8)

5 (2, 10)

0.15

Pain rating index ordinal categories, n (%)

0.53

No pain

35 (14)

16 (15)

19 (14)

Mild pain

77 (32)

41 (37)

36 (27)

Discomforting, distressing, horrible, or excruciating pain

116 (48)

49 (45)

67 (50)

Fatigue (FSI) N

230

106

124

Median score [IQR]

52 (25, 81)

49 (21, 79)

54 (28, 84)

0.18

Functional status (mHAQ) N

235

106

129

Median score [IQR]

0.1 (0.0, 0.5)

0.1 (0.0, 0.5)

0.1 (0.0, 0.4)

0.62

Functional status categorical score, n (%)

0.87

Normal (<0.3)

145 (59) 90 (37)

66 (60) 40 (36)

79 (59) 50 (37)

Mild, moderate, or severe (0.3 to >1.8)

Health status (SF-12) PCS-12 score, median [IQR] MCS-12 score, median [IQR]

42.8 (33.6, 51.7) 49.9 (39.3, 56.0)

43.6 (33.7, 53.5) 49.0 (41.3, 55.4)

42.2 (33.4, 50.3)

0.48

51.2 (36.7, 57.7)

0.98

2022;0:1–9. doi: 10.1136/ard-2022-223439 Ann Rheum Dis , et al. Patel NJ

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