2023 Rheumatology at BMJ

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Supplemental material

Ann Rheum Dis

Supplementary Table 5. Patient-reported outcomes among patients with PASC following breakthrough versus non-breakthrough COVID-19 infection Characteristic p-value

All patients with PASC (N=137)

PASC following breakthrough COVID-19 infection (N=48)

PASC following non- breakthrough COVID-19 infection (N=89)

Pain (SF-MPQ) N

124

45

79

Median score [IQR]

7 (3, 12)

6 (2, 13)

7 (3, 11)

0.74

Pain rating index ordinal categories, n (%)

0.32

No pain

12 (9)

2 (4)

10 (11)

Mild pain

31 (23)

13 (27)

18 (20)

Discomforting, distressing, horrible, or excruciating pain

83 (61)

30 (63)

53 (60)

Fatigue (FSI) N

128

45

83

Median score [IQR]

67 (36, 90.5)

66 (33, 89)

67 (36, 92)

0.66

Functional status (mHAQ) N

129

45

84

Median score [IQR]

0.4 (0.0, 0.8)

0.3 (0.1, 0.8)

0.4 (0.0, 0.7)

0.32

Functional status categorical score, n (%)

0.85

Normal (<0.3)

64 (47) 65 (47)

23 (48) 22 (46)

41 (46) 43 (48)

Mild, moderate, or severe (0.3 to >1.8) Health status (SF-12) Physical Component Summary (PCS-12) score, median [IQR] Mental Component Summary (MCS-12) score, median [IQR] Persistent symptoms at time of survey, n (%) Fatigue/malaise

38.3 (31.4, 47.4)

37.6 (31.5, 46.1)

38.8 (31.2, 48.1)

0.70

46.4 (38, 54.9)

45.5 (39.5, 54.0)

46.8 (36.7, 55.8)

0.63

39 (28)

16 (33)

23 (26)

0.43

Anosmia

25 (18) 22 (16)

6 (13) 5 (10)

19 (21) 17 (19)

0.25 0.23

Dysgeusia

Dyspnea and/or cough

15 (11)

4 (8)

11 (12)

0.57

Nasal congestion or rhinorrhea

17 (12)

8 (17)

9 (10)

0.29

2022;0:1–9. doi: 10.1136/ard-2022-223439 Ann Rheum Dis , et al. Patel NJ

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