2023 Rheumatology at BMJ

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Supplemental material

Ann Rheum Dis

Supplementary Table 6. Self-reported systemic rheumatic disease activity and flare following COVID- 19 infection.

Non- breakthrough COVID-19

Breakthrough COVID-19

All rheumatic disease patients (N=280)

p-value

infection (N=116)

infection (N=164)

Self-reported SARD flare after COVID-19, n (%) Timing of self-reported SARD flare after COVID-19, n (%)

115 (41)

46 (40)

69 (42)

0.71

0.19

<1 week

32 (11)

17 (15)

15 (9)

1-4 weeks

49 (18)

20 (17)

29 (18)

4-12 weeks >12 weeks

26 (9)

7 (6) 2 (2)

19 (12)

8 (3)

6 (4)

Participant global assessment of disease activity before COVID-19 onset, mean ± SD Participant global assessment of disease activity at time of survey, mean ± SD Disease activity by RAPID-3 at time of survey Median score [IQR]

7.6 (2.3)

7.6 (2.4)

7.6 (2.3)

0.98

6.7 (2.7)

6.8 (2.5)

6.6 (2.8)

0.41

3.0 (1.3, 4.7)

3.0 (1.3, 4.7)

3.3 (1.3, 4.7)

0.48

Categorical score, n (%)

0.86

Remission (0)

17 (6)

6 (5)

11 (7)

Near remission (0.3-1.0) Low severity (1.3-2.0) Moderate severity (2.3- 4.0) High severity (4.3-10.0)

37 (13) 34 (12)

17 (15) 13 (11)

20 (12) 21 (13)

84 (30)

31 (27)

53 (32)

82 (29) 53 (32) COVID-19, coronavirus disease 2019; RAPID3, Routine Assessment of Participant Index Data 3; SARD, systemic autoimmune rheumatic disease 29 (25)

2022;0:1–9. doi: 10.1136/ard-2022-223439 Ann Rheum Dis , et al. Patel NJ

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